Back to Blog
Abcd method6/26/2023 ![]() However, upper gastrointestinal tract endoscopy and gastric fluoroscopy are costly and inconvenient for people undergoing screening. In Korea and Japan, a mass screening program that uses upper gastrointestinal tract endoscopy and gastric fluoroscopy has been introduced for the early detection of gastric cancer. The prognosis of patients with gastric cancer depends on the tumor stage. Gastric cancer is one of the major causes of cancer-related death worldwide, and almost 990,000 cases of gastric cancer are detected annually. However, further studies will be required to provide a definitive conclusion. This method might be a supplementary screening tool for both gastric adenoma and gastric cancer. The modified ABCD method using two different cutoff values according to the H. pylori antibody status was useful for predicting the presence of gastric neoplasms. A higher group grade was associated with a significantly higher proportion of gastric neoplasms. The optimal cutoff values of the PG I/PG II ratio for predicting gastric neoplasms were 3.1 for H. pylori antibody negative patients and 4.1 for H. pylori antibody positive patients. The PG I/PG II ratio was lower in patients with gastric neoplasms than in patients without these lesions (gastric adenoma vs gastric cancer vs no neoplasm, 3.7 ± 2.0 vs 3.8 ± 1.8 vs 4.9 ± 2.1, P < 0.001). Patients were classified into the following four groups: H. pylori antibody negative and normal PG level (group A), H. pylori antibody positive and normal PG level (group B), H. pylori antibody positive and low PG level (group C), and H. pylori antibody negative and low PG level (group D). ![]() We reviewed 562 patients who had undergone upper gastrointestinal tract endoscopy and whose serum IgG anti- Helicobacter pylori antibody, gastrin, and pepsinogen (PG) I and PG II data were available. We aimed to devise a modified ABCD method for predicting gastric neoplasms. It is unclear whether the ABCD method can predict the risk of gastric neoplasms, including gastric adenomas, as observed for gastric cancer. The ABCD screening method was developed for risk stratification of gastric cancer.
0 Comments
Read More
Leave a Reply. |